Recent work reveals that GPX4-controlled ferroptosis in neutrophils drives systemic autoimmunity by unleashing redox-active iron, which amplifies inflammatory and immune activation, a hallmark of SLE (216)
Madeddu, C., Dessi, M., Panzone, F., Serpe, R., Antoni, G., Cau, M
10.1371/journal.pone.0026915 6
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Immunoassays performed in the mouse model of APAP toxicity determined the relationships between tissue adducts and toxicity, as measured by pathologic examination of the liver tissues and serum ALT levels (Potter et al
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