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Advantages of crystallographic fragment screening: Functional and mechanistic insights from a powerful platform for efficient drug discovery

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A standard calorie deficit typically involves reducing intake by around 600 kcal per day, whereas a very low-calorie diet (VLCD) involves consuming below 800 kcal per day and carries a higher risk of nutritional deficiencies and digestive disturbance

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A prospective therapeutic strategy: GPX4-targeted ferroptosis mediators

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