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doi: 10.1016/j.scitotenv.2023.165992 96 Guerrero RamrezJ

For instance, reduced expression of PER1 and CRY1 has been associated with higher tumor grade and poor prognosis 27

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2.4 Metabolomics as a complement to residue detection Routine residue detection methods [e.g., gas chromatographymass spectrometry (GCMS), liquid chromatographytandem mass spectrometry (LCMS/MS), and immunoassays] provide quantitative data on known pesticide compounds but are limited in scope: they often do not focus on unknown transformation products, conjugated residues, or the dynamic biological impact of exposure