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User protocols typically employ 0.25 to 0.5 mg daily via subcutaneous injection near the injured tendon for four to eight weeks

Always consult your healthcare provider before beginning any new supplement

Formulation alternatives may provide relief: Different tablet formulations with alternative inactive ingredients may be better tolerated Liquid preparations can be easier to tolerate and allow flexible dosing Intramuscular injections completely avoid the gastrointestinal tract and are particularly useful for those with absorption issues (such as pernicious anaemia or malabsorption) or persistent oral intolerance Review inactive ingredients: Examine the supplement label for potential irritants or allergens

That said, consult your doctor if you have serious health issues

A 2025 systematic review reported 7 of 12 maintained improvement beyond 6 months

It solves the practical problem that these items are typically sold in bulk quantities far exceeding what a single research protocol requires, and sourcing them individually from multiple suppliers creates unnecessary complexity