While emerging evidence, including preclinical studies, early-phase trials, and limited clinical series, suggests that KD may help overcome treatment resistance by suppressing the PI3K/Akt/mTOR pathway, reducing insulin-like growth factor-1 (IGF-1) signaling, and enhancing cancer cell susceptibility to chemotherapy and targeted therapies, robust data from large, randomized controlled trials (RCTs) remain sparse
This led to a heated debate to answer what could have been the cause of such change
The surgical treatment of osteoarthritis
NADPH oxidase and redox status in amygdala, hippocampus and cortex of male Wistar rats in an animal model of post-traumatic stress disorder
!Chemotherapy drugs - GHK-Cu promotes cell growth and blood vessel formation, which could theoretically interfere with cancer treatment
Zhou Q, Homma KJ, Poo MM (2004)