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The efficacy and safety of apremilast, etanercept and placebo in patients with moderate-to-severe plaque psoriasis: 52-week results from a phase IIIb, randomized, placebo-controlled trial (LIBERATE) J Eur Acad Dermatol Venereol

REFERENCES 1 AdamJ.HatipogluE.OFlahertyL.TernetteN.SahgalN.LockstoneH.et al (2011)

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Reported pathways include TGF- signaling, antioxidant defense (superoxide dismutase, glutathione peroxidase), extracellular-matrix gene expression (collagen types I and III, decorin, perlecan), and inflammatory cytokine modulation

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