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The cigars head is the often-capped area, which touches your lips

Acknowledgements The authors gratefully acknowledge the comments made by the reviewers as well as the editor on earlier versions of this manuscript

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Moreover, the TGF-1/Smad2.3 signalling pathway is strongly implicated in endothelial to mesenchymal transition (EndMT) which plays a key role in the pathogenesis of COPD [129,130,131]

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& Wechsler, H