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The latter is referred to as the senesence associated secretory phenotype (SASP) and this is considered to be driving many aspects of functional decline

These data suggested that VRK2-deficient PC cells underwent ferroptosis following GSH inhibition

The low-selenium condition in combination with three mycotoxins, deoxynivalenol (DON), nivalenol (NIV), and T-2, yielded pro-catabolic changes and hypertrophic phenotype of chondrocytes, as evidenced by the loss of aggrecan and type II collagen (COLII) and the increase in COLX and matrix metalloproteinases (MMPs) expression, respectively 71

doi: 10.1097/MD.0000000000002137 76 SderstrmKSteinEColmeneroPPurathUMller-LadnerUde MatosCTet al

Dermatol Pract Concept 12(4):e2022179

The adducts were screened by the sitting-drop vapour diffusion method using commercially available screens from Molecular Dimensions and Qiagen, dispensed by the Mosquito robot (TTP Labtech)