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In a model of diabetes, ferrostatin-1 reduces accumulation of lipid peroxides and infiltration of macrophage, and increases the number of insulin-associated cells, protecting islets from streptozotocin (STZ)-induced damage ( 5.4 AGEs High availability of glucose and/or lipids is characteristic of diabetes and obesity, which is responsible for the increased production of highly reactive carbonyl compounds ( 5.5 HO-1 Heme oxygenase-1 (HO-1), also known as heat shock protein-32 (HSP 32), is an anti-inflammatory, antioxidant and cytoprotective enzyme

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The yeast solids are removed by centrifuging or filtration