doi:10.1016/0003-9861(79)90343-6
This mechanism suggests the peptide can restore youthful patterns of gene expression in senescent cells
Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrientssuch as glutathionethat provide antioxidant activity
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Higher incidence of hepatotoxicity was observed in patients with advanced HIV infection which was probably caused by increasing the oxidation to toxic metabolites by the P 450 system [1,111]