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The limited absorption of the nasal cavity restricts the amount of drug being effectively absorbed, making class I drugs (high permeability, high solubility), according to the Biopharmaceutics Drug Disposition Classification System (BDDCS), particularly suitable for nasal delivery (Ugwoke et al., 2001)

Acetaminophen attenuates error evaluation in cortex

Indeed, recent findings in depression suggest that the glutamate-glutamine ratio may be a particularly informative measure (Yuksel & Ongur, 2010)

Some IC/BPS patients have bladder-centric phenotypes (e.g., Hunner lesions, small bladder capacity, pain improved with intravesical local anesthetics)

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