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PMID 29167919

Since taking lipoic acid with a meal decreases its bioavailability, it is generally recommended that lipoic acid be taken 30 min prior to a meal (see also Metabolism and Bioavailability) (8)

Take it in the morning and midday, ideally on an empty stomach

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Could its potential non-metabolic functions or subcellular localizationsuch as within lysosomes or other organellesmodulate lysosomal pH homeostasis and death susceptibility in a context- or tumor-type-specific manner

- Discontinue use if any adverse reactions occur