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Biomodulation of cancer chemotherapy for metastatic colorectal cancer: a randomized study of weekly low-dose irinotecan alone versus irinotecan plus the oncostatic pineal hormone melatonin in metastatic colorectal cancer patients progressing on 5-fluorouracil-containing combinations

Key scientific mechanisms: GHK-Cu stimulates fibroblasts to increase production of collagen, elastin, and hyaluronic acid crucial for skin firmness, elasticity, and tissue repair

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It works by reducing melanin production, which results in a lighter and more even skin tone

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FIC calculation showed that vitamin C had a synergistic effect with most antibiotics (Levofloxacin, Meropenem, Ceftazidime and Nitrofurantoinm)