N-Acetyl L-Cysteine (NAC) is a modified form of the amino acid cysteine that serves as a precursor to glutathione production in the body
GSSG is then reduced to GSH by glutathione reductase (GR) using reducing equivalent provided by NADPH
These include increasing muscle mass (1,49, 55,), reducing body fat (49, 50, 51), helping to maintain muscle mass during weight loss (51), suppressing appetite to aid fat loss, increasing metabolism (50), improving immune function, reducing blood pressure (52), reducing unhealthy blood fats (53), improving blood glucose levels in type 2 diabetics, and increasing the production of glutathione, the bodys master antioxidant (54)
These treatments include NAC, melatonin, coQ10, thiamine, riboflavin, niacin B3, vitamins B6 and B12, folate, vitamins A, C, D and K, calcium, phosphorus, magnesium, sodium, potassium, chloride, iron, zinc, copper, selenium, iodine, vitamin E, vitamin K, L-arginine, inositol, biotin, pantothenic acid, eicosatetraenoic acid (EPA), docosahexaenoic acid (DHA) and various combinations of the above (188)
Some inherited metabolic disorders (pyridoxine-dependent conditions) may require very large daily doses
Increased Homocysteine, Homocysteine-Thiolactone, Protein Homocysteinylation and Oxidative Stress in the Circulation of Patients with Eales Disease. Annals of Clinical Biochemistry, vol