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Its core vulnerability is chemical: the active sulfhydryl group (SH) on cysteine oxidises rapidly on exposure to gastric acid, digestive enzymes, heat, and light

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Additionally, GHK-Cu promotes the synthesis of glycosaminoglycans, complex molecules that enhance hydration, elasticity, and skin firmness

This in vitro synergy confirmed that the interaction occurs at the somatotroph level, independent of hypothalamic factors, and reflects direct convergence of receptor signaling pathways on the GH secretory machinery