Cyanocobalamin is sparingly soluble in alcohol and water (1 in 80 of water), but insoluble in chloroform, acetone, and ether
However, no published research directly compares continuous versus cycled protocols
Retailers and groups like the Global Retailer and Manufacturing Alliance (GRMA) can help by setting policies against the sale of these research chemicals until they are managed in a way that ensures proper consumer protection and quality control
Some compounding pharmacies also offer oral formulations, though absorption rates are lower with oral administration
If reticulocytes have not increased after treatment or if reticulocyte counts do not continue at least twice normal as long as the hematocrit is less than 35%, diagnosis or treatment should be reevaluated
Always follow your own institutions handling protocols for research compounds.