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Clouds of smoke could be seen from the school building, but by the time the duty teacher reached the circle on the cricket field, the shared cigarette had been buried deep into the soil below the neatly cut outfield

Extracts from tobacco rods were serially diluted and superfused over HEK293T cells expressing the human TRPM8 cold/menthol receptor activated by menthol, WS-3 and other synthetic cooling agents, measuring activity by Calcium-microfluorimetry as published (Supplementary file) 3

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