65 Nrf2 and its downstream molecules (NQO1, HO-1) were significantly elevated in endometriotic lesions, and these antioxidants mitigated cell death by scavenging ROS (O 2 and OH)
Because they're unstable, they can take electrons from other cells or react negatively with the molecules in a cell, setting off a chain reaction that terminates in apoptosis, or cell death.11 Oxidative stress can stem from various causes, such as smoking, drinking, environmental pollution, exposure to sunlight, and mental/physical stress.12 Although the body needs pro-oxidants, they can cause several detrimental health effects when present in overabundance without enough antioxidants to counter them, such as:13 Cancer Rheumatoid arthritis Kidney diseases Cardiovascular diseases Neurological diseases Respiratory diseases Psychological disorders Age-related degeneration Insider Tip: Glutathione is pronounced glu-ta-THI-one, with the stress on the third syllable
Learn more in our KPV peptide benefits guide
Mechanisms of Action: The Core Difference This is where the two compounds genuinely diverge
These include oxidation of glucose in the pentose phosphate pathway, oxidation of isocitrate by isocitrate dehydrogenase, oxidation of malate by malic enzyme, and oxidation of methylenetetrahydrofolate [48]
I was like whoa, that's wild