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We selected pAcF as the handles for constructing conjugates instead of other chemistry such as azide mediated click chemistry as the cyclopropane-tetrazine ligation employed in the pAcF system demonstrates superior bioorthogonality compared to azide-alkyne cycloadditions, effectively minimizing off-target reactions in complex cellular environments

In the current review, garlic and its major bioactive components along with their biological function and mechanisms of action for their role in disease prevention and therapy are discussed

6 Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA

Pan Y, Zhang H, Li M, He T, Guo S, Zhu L, Tan J, Wang B

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However, since iron is a cellular transition element and its ionic forms participate in electron transfer reactions, it can also produce free radicals