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Tung TT, Quoc TN (2021) Discovery of novel -turn mimetic-based peptides as novel quorum sensing inhibitors of gram-negative bacteria

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Interventions targeting lipid peroxidation preserve NE integrity, extend lifespan in worms and ameliorate senescence-associated phenotypes in human fibroblasts and monkey cells mimicking HutchinsonGilford progeria syndrome disease

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Its core pathogenesis involves the interplay of three key processes: immune dysregulation that is characterized by Treg dysfunction and B-cell hyperactivation, vascular endothelial injury and dysfunction, and abnormal fibroblast proliferation (226)