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8 DiFrancisco-Donoghue J1, Lamberg EM, Rabin E, Elokda A, Fazzini E, Werner WG

NAC reduces IL-17-induced activation of the mTOR/JNK/NF-B (nuclear factor B) pathway to regulate the expression of RANKL in synovial fibroblasts and osteoblasts, preventing inflammation and bone destruction during RA [135]

Animals were subject to a timed-mating protocol, whereby prior exposure of females to dirty bedding from males allowed for stimulation and synchronization of the females estrous cycles through the Whitten Effect (Jemiolo et al, 1986)

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Competing interests The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript