Biochemistry 70 , 222230 (2005)
[16] [17] adenosylcobalamin cyanocobalamin, the adenosyl ligand in vitamin B 12 is replaced by cyanide
These data were confirmed by a lower TEER in Ussing chambers (81, 82) and a decreased number of tight-junction strands shown by freeze-fracture electron microscopy (83)
Therefore, a more effective approach to improve bioavailability and increase blood levels of 25(OH)VD would be to consume both LC and VD nutrients together rather than relying solely on high-dose vitamin D supplementation
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Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury