This antioxidant prevents the cells in the body from being damaged and supports the functions necessary for a healthy life
doi: 10.1530/acta.0.1140497 64 ThillyCHContempreBVanderpasJB
Therefore, enhanced glutaminolysis might eventually contribute to the initiation and progression of cancer by stimulating cell growth via the mTORC1 pathway and enhancing aerobic glycolysis while disrupting the proper elimination of misfolded proteins, damaged DNA and organelles through the inhibition of autophagy and the DNA damage response 166
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Together, these findings highlight a distinct metabolic signature in ME/CFS, where energy production pathways may fail to respond efficiently to physical exertion, potentially driving exacerbation of symptoms seen in PEM
Fan L, Feng Y, Chen GC, Qin LQ, Fu CL, Chen LH