what produces glutathione in the body Newly revealed amino acid function could be used to boost antioxidant levels Glutathione: Master Antioxidant, Reducing Oxidative

Different hypotheses have been brought forward to explain the evolving LB pathology across the brain, including: retrograde transport of pathological -synuclein via neuroanatomical networks, -synucleins prion-like behavior, and cell- or region-autonomous factors 2,3

Heatmap showing viability of H9C2 cells treated with the following ferroptosis inducers: RSL3 (50 nM), erastin (2 M), ML210 (0.3 M), ML162 (0.3 M), FIN56 (0.5 M), BSO (100 M) and FINO 2 (5 M)

doi:10.1186/s13063-016-1399-9 15

Similarly, PAT-1251 would inhibit both LOXL2 and LOXL3 at 10 M (IC 50 (LOXL2) = 0.87 M, IC 50 (LOXL3) = 1.38 M), but inhibit less than 10% inhibition of diamine oxidases (hDAO) and monoamine oxidase (hMAO) 41

Rapamycin What is it

J Biomol Struct Dyn 41:123 Kurrikoff K, Aphkhazava D, Langel (2019) The future of peptides in cancer treatment