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Initially investigated for its potential to treat neurodegenerative diseases like Alzheimers and Parkinsons, this small synthetic peptide is known to bind with high affinity to hepatocyte growth factor (HGF) and its receptor c-Met, thereby promoting neuronal differentiation, dendritic branching, and synaptic plasticity

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J Biochem Mol Toxicol 38(1):e23618 Choi W, Choe S, Lin J, Borchers MT, Kosmider B, Vassallo R et al (2020) Exendin-4 restores airway mucus homeostasis through the GLP1R-PKA-PPARgamma-FOXA2-phosphatase signaling

However, there are significant precautions and concerns regarding its use, particularly related to tumor growth and the lack of rigorous human studies

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