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Stampfer MJ, Malinow MR, Willett WC, Newcomer LM, Upson B, Ullmann D, Tishler PV, and Hennekens CH (1992)

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The test is usually terminated once the patient experiences a 20% decrease in breathing ability, or a maximum test dose of methacholine is achieved (American Lung Association - Methacholine Challenge Test)

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