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A recent systematic review and meta-analysis of 25 observational studies found proton-pump inhibitor use was associated with a small increased risk of vitamin B 12 deficiency

It binds to transport proteins, primarily transcobalamin II , which delivers B12 to tissues throughout the body

Low energy is more than annoying

If you previously tried semaglutide and discontinued due to nausea, the addition of B12 might allow successful treatment

It is a key nutrient in the production of red blood cells, which are crucial for transporting oxygen throughout the body

Currently, the phase 3 trial is expected to continue through the end of 2025 (4), and afterwards the drug application would be submitted to the Food and Drug Administration (FDA) for approval