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The implementation of the EU Health Technology Assessment (HTA) Regulation is increasing the focus on patient-centered outcomes and real-world evidence to complement clinical trial data in reimbursement and access decision-making

Murthy, V

251 In Salmonella , acute Zn II toxicity transcriptionally induces a Co II toxicity response orchestrated by the Co/Ni sensor, RcnR, while conversely, acute Co II toxicity triggers a Zn II toxicity response regulated by the Zn II efflux activator ZntR, leading also to repression of the Zur regulon

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Pharmacol.,1987253 EOF306 EOF 128

Transaminase transfers amino groups from glutamate to oxaloacetate, producing -ketoglutarate and Asp