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Existing evidence is limited to preliminary observations from small cohorts and short follow-up, which does not allow for firm clinical conclusions (216)

demonstrated for the first time that epithelial cell production of H 2 O 2 preceded the recruitment of leucocytes, and in particular that DUOX was the main source of H 2 O 2 at the wound site and inducer of rapid leucocyte recruitment from long distances 17

The protein of interest can be cleaved off the GST tag by site-specific protease if desired

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