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Insulin resistance and changes in the blood coagulation-fibrinolysis system after a glucose clamp technique in patients with type 2 diabetes mellitus
By selectively inhibiting NNMT an enzyme central to energy regulation and fat metabolism this compound has demonstrated, in preclinical studies, the capacity to elevate intracellular NAD and SAM levels, suppress lipid accumulation in adipocytes, and reduce white adipose tissue mass in diet-induced obese mouse models
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