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MacPherson JC, Comhair SA, Erzurum SC, Klein DF, Lipscomb MF, et al: Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species

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In RA synovial fluid (SF), it is accepted that abundant activated neutrophils with a specific phenotype were characterized by an increased oxidative burst, elevated cytokine secretion, and delayed apoptosis [10]

Further proteomic analysis of the epididymis and sperm revealed that proteins essential in metabolism, ROS production, stress, inflammation and in the regulation of reproductive function were adversely affected