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COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

Overall, current evidence suggests that selenium supplementation may hold greater potential in individuals with low selenium status, whereas its generalized use remains to be validated in larger and more rigorously designed trials