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Human endometriosis tissues reportedly exhibit minimal apoptosis29,37

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[DOI] [PubMed] [Google Scholar] 6.Kraemer W.J., Volek J.S., French D.N., Rubin M.R., Sharman M.J., Gmez A.L., Ratamess N.A., Newton R.U., Jemiolo B., Craig B.W., et al

In addition, peptides (such as FRAF) form a multi-level inhibition network by targeting MITF, TYR and TYRP1/2, and its mechanism goes beyond single target intervention: FRAF forms hydrogen bonds with ASP431 and ALA384 of MITF, blocking the combination of MITF and target gene promoters (such as TYR and TYRP1) and inhibiting the expression of melanin synthesis-related enzymes

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