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Mice and tumor-bearing mouse model C57BL/6 mice (male, 7 weeks) were maintained in a specific pathogen-free facility

Notably, in models combining metabolic dysfunction and neurodegeneration, AX reversed diabetes-induced cognitive deficits while concomitantly improving hepatic insulin signaling and modulating brain nutrient-sensing and inflammatory pathways, highlighting the tight interplay between peripheral and central metabolic regulation [88]

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Trisilicates also can cause metabolic derangement and should not be used for extended periods

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