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Behav Brain Res (2017) 316:110

(2019) 14:e0226927

Bork, F

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Finally, the coq10 yeast mutant, which has a near wild-type content of CoQ 6 in the stationary phase but inefficient CoQ 6 biosynthesis during the log phase (30% relative to wild type), was also found to be sensitive to Lnn exposure during mid-log phase (though less than coq3 mutant), and, consistently, Lnn-treated coq10 mutants showed significantly increased lipid peroxidation levels compared to the wild type (331)

In our study, we did not observe an increase in loose stools in NAC-treated animals during daily monitoring, consistent with previous research showing no toxicity after 30 days of high-dose NAC (1200 mg/kg/day) in rats [109]