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Matrixyl 3000 combines two peptides - palmitoyl oligopeptide and palmitoyl tetrapeptide-7 - to maximize collagen synthesis while reducing inflammation

In addition to enzymatic L-lactylation utilizing lactate as a lactyl donor and involving enzymes including writers (lactyltransferases), readers (lactylation-binding enzymes), erasers (delactylases), and lactyl-coenzyme A (lactyl-CoA) synthases, non-enzymatic D-lactylation derived from the glyoxalase II substrate S-D-lactoylglutathione (SLG) has also been identified

doi: 10.1038/s41598-024-60413-y 63 MuratCKayaAKayaDErdoanMA

Upregulates genes involved in antioxidant defense (superoxide dismutase, catalase), tissue repair (collagen synthesis, matrix metalloproteinases), anti-inflammation (suppressing TNF-, IL-6)

HO-1 as an important regulator of oxidative stress and inflammation, also plays an important role in diabetic kidney apoptosis

NFB, Nuclear Factor kappa B