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By combining amylin (cagrilintide) and GLP-1 (semaglutide), CagriSema achieved a 20,4% reduction in treatment policy and up to a 22,7% reduction per-protocol at 68 weeks in REDEFINE 1 (n=3417), which is greater than each compound taken alone and on par with the best single agents

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Key takeaways CagriSema combines semaglutide 2.4 mg (a GLP-1 agonist) and cagrilintide 2.4 mg (an amylin analogue) in a single weekly injection