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doi: 10.1016/j.ebiom.2019.02.050 139 HernandezPGronkeKDiefenbachA

Obesity represents itself as a challenge for hypothalamus-pituitary-thyroid axis since it has been hypothesized that hyperleptinemia, that often characterizes these patients, may increase the expression of TRH gene and thus TSH secretion [194]

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(2025) When sexual stimulation activates the CC, the non-adrenergic non-cholinergic nerve endings and L-arginine within the endothelial cells can promote the release of NO from nitric oxide synthase (NOS) (such as endothelial NOS and neuronal NOS) [32]

Additionally, we discuss novel developments in drug delivery strategies to transport small molecules, biologicals or cellular therapeutics across the BBB