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Revised April 2021

In three consecutive enzymatic reactions, G6PDH (reaction 1), followed by 6-phosphogluconolactonase (6PGL, reaction 2) and 6PGDH (reaction 3), glucose-6-phosphate (G6P) is catabolised supplying cells with ribulose-5-phosphate maintaining the antioxidative power by generating 2 NADPH molecules

Due to the large number of ANOVA tests, P-values for main effects and interactions were corrected using the false discovery rate method

gingivalis is known to downregulate host antibacterial responses such as reducing IL-1, IL-6 and IL-8 levels and is capable of infecting and living within cells such as gingival fibroblasts, microglia, astrocytes and neurons (Dominy et al., 2019

Standard dosing protocol: Cyanocobalamin 1000mcg/Ml-Picture Courtesy: Dr