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Marcello Allegretti, Domp spa, Italy Copyright 2014 Tuzova, Jean, Hughey, Brown, Cruikshank, Hiratake and Joyce-Brady

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In breast cancer cell lines, 4-OXO-DHA induced PPAR and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) but inhibited the activity of NF-B and suppressed PI3K and mTOR signaling

The authors concluded that PTMs may occur at the level of this N-terminal region

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