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In-vitro fibroblast studies indicate that GHK-Cu upregulates transcription of collagen and elastin genes and supplies copper as a cofactor for lysyl oxidase, the enzyme that cross-links these matrix proteins

Oestrogenic endocrine disruptors in the placenta and the fetus

Barbaresi, W

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If so, NET-directed diagnostics (e.g., circulating MPODNA or citrullinated histone H3) and targeted interventions (DNase, PAD4 inhibitors, anti-platelet strategies that disrupt plateletneutrophil conjugation) could represent novel approaches to mitigate CV risk in PCOSan avenue that urgently warrants prospective, mechanism-focused clinical investigation (see Fig

Atorvastatin attenuates ferroptosis-dependent myocardial injury and inflammation following coronary microembolization via the hif1a/ptgs2 pathway