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NRF2 plays a critical role in this process by upregulating the expression of genes involved in the synthesis of -GC, thereby increasing the overall production of GSH [34]

Rodent hepatocarcinogens are usually hepatotoxins

Oxidative stress occurs when free radicals damage cells and is at the root of many diseases

CNN News 'Like a war zone': France evacuates 20,000 due to wildfires Black smoke darkened the skies and crackling flames roared through pine trees in a forest in southwest France on Thursday as wildfires have forced more than 20,000 residents and holidaymakers to flee.Wisps of smoke rose from charred or crackling tree trunks between Le Porge and the village of Lege-Cap-Ferret to the south

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Authors contributions Review concept (GYW), information collection, drafting of the manuscript (BT), and revision of the manuscript (GYW, BT)