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R389Q mouse model, suggesting that inflammation could be a major component of the pathology in the neurodegeneration of FDXR mutations [86] NDUFV1 deficiency (OMIM # 618225) NADH: ubiquinone oxireductase flavoprotein 1 (NDUFV1) is a 51-kDa highly conserved nuclear encoded subunit comprising the electron input (N) functional module of Complex I [87] )

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