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Wake R, Miyaoka T, Inagaki T, Furuya M, Ieda M, Liaury K, Kishi K, Horiguchi J (2013) Yokukansan (TJ-54) for irritability associated with pervasive developmental disorder in children and adolescents: A 12-week prospective, open-label study

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L-arginine increases the cellular GPX4 content and decreases ROS production through the arginase-1 signaling pathway, suggesting its involvement in the regulation of ferroptosis [50]

The symptoms overlap significantly, and both can be influenced by genetic variants in histamine-degrading enzyme genes