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the direction of this modulation was age- and region-dependent

The reconstitution of recombinant mitochondrial dicarboxylate carrier into proteoliposomes showed a transport activity for GSH with kinetics, substrate specificity, and inhibitor sensitivity similar to those observed in rat kidney proximal tubules (77)

However, it's crucial to approach glutathione supplementation, especially for skin and hair benefits, with caution

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( n ) Cells were treated with olaparib (n = 3 technical replicates representative from 3 independent experiments in each cell line)