Journal of Inflammation (London, England), 9(1), 28 10.1186/1476-9255-9-28 [DOI] [PMC free article] [PubMed] [Google Scholar] Hrelec, M
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4.1.3 Indirect protection of GPX4 by regulating iron homeostasis and substrate supply Beyond directly targeting GPX4 or its related pathways, indirect strategies have also garnered attention, primarily including reducing local iron load for example, using iron chelators (Wu et al., 2023), decreasing oxidizable PUFAs substrates in membrane phospholipids through dietary intervention or locally altering lipid composition (Li Y
9 BPC-157 modulates the Src-Caveolin-1-eNOS pathway, promoting nitric oxide production and vasodilation, which are essential for vascular health and angiogenesis
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