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[DOI] [PubMed] [Google Scholar] 117.Estrela J.M., Ortega A., Obrador E

TRIUMPH-CVOT: cardiovascular outcomes trial, approximately 10,000 participants with established CVD, primary endpoint major adverse cardiovascular events (MACE), timeline 3 to 4 years

Safety Considerations in Canine Subjects Available research suggests: Toxicity data: Limited long-term toxicology studies in dogs specifically Side effects: Research in rodents generally reports minimal adverse effects at studied doses Drug interactions: Potential interactions with other medications not well characterized Monitoring: No established protocols for monitoring dogs receiving BPC-157 The absence of comprehensive safety data in dogs represents a significant knowledge gap

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