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PMID: 26752456

Major depressive disorder (MDD) and related depressive conditions exhibit elevated oxidative stress markers, reflecting increased oxidative damage to lipids, proteins, and DNA, as well as a relative depletion of antioxidants in plasma and peripheral tissues (3537)

This imbalance contributes to airway inflammation, airway hyperreactivity, and epithelial injury, which are hallmarks of airway disorders

Conversely, LC3-positive extracellular vesicles (EVs) can promote lung metastasis in breast cancer patients and the number of LC3-positive EVs positively correlates with disease progression (315)