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Intra-articular therapy with superoxide dismutase (orgotein) or cortisone in rheumatoid and arthritic inflammatory finger joint lesions

Cu/Zn-superoxide dismutase and wild-type like fals SOD1 mutants produce cytotoxic quantities of H 2 O 2 via cysteine-dependent redox short-circuit

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doi:10.7554/eLife.02523 Sato H, Tamba M, Ishii T, Bannai S (1999) Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

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This aggressive metabolic shift, while beneficial for fat loss, places demands on the body that warrant additional support