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Activation of the kynurenine pathways is often associated with reduced free circulating (reviewed by Hazrati et al., 2024) and brain tryptophan levels (Hazrati et al., 2024

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Cisplatin formulated was dissolved to a concentration of 3.33 mM in either saline or PBS

37 To obtain these cells, healthy teeth were collected from adult donors aged 1835 years at the Dental Clinic of Beijing Stomatological Hospital, following written informed consent for participation in this study

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